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Solution of a Variational inequality for charge transport DNA model with vibrational and rotational coupling motion (#1483)

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Date of Conference

July 16-18, 2025

Published In

"Engineering, Artificial Intelligence, and Sustainable Technologies in service of society"

Location of Conference

Mexico

Authors

Cortez Gutierrez, Milton Milciades

Cortez Gutierrez, Hernan Oscar

Abstract

This paper is concerned with the solution of a variational inequality for charge transport DNA model with vibrational and rotational coupling motion. For that we use the theory of semigroup according to [9] to rewrite in vector form the system obtained from the dynamics of the Peyrard-Bishop model for vibrational motion of DNA dynamics, which has been extended and analysed by [6], that is, Ut =AU +F(U) U(0) = U0 (1) This system given by (2) stand for an initial value problem, which we show that, under suitable assumptions of the operator A and on the nonlinearity F the system supports a single global weak solution satisfying the given initial condition, for that one, we consider the Sobolev spaces which will solve the Cauchy problem. The ideas of Elena D´ıaz [4] have really been followed, who considers the Peyrard-Bishop-Holstein model, which introduces a description of polaronic effects for the transport of electrical charge in DNA. Consequently, a Schr¨odringer equation is added for electrical transport, whose indicator is the amplitude probability for an electric charge located in the nth nucleotide. Likewise, in the vibrational part, the Peyrard-Bishop model has been maintained in its continuous form, which has as its starting point the discrete form in the reference of [6].

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